Research Fellow- Admixture Characterization and Environmental Exposure Impact in Asthma




TITLES SUPERVISED: Research Assistants, Data Analysts, Biostatisticians


PURPOSE OF POSITION: To learn to conduct independent research and support the independent research of others in a Medical Center dedicated to the care of infants, children, and adolescents.

TheMersha Lab has an opening for a Research Fellow who will be involved in a combined computational and applied genetics project, focused on the development and implementation of ancestry (admixture) based detection and characterization of genetic and environmental exposure risk factors in asthma. The primary goal is to develop and implement statistical methods to analyze high-throughput sequence and array data and maintain large datasets linked to clinical data.

·Perform analysis and experiments
Design, execute, and record analysis and experiments; apply standard scientific protocols to research, and improve current methods and evaluate innovative techniques. Develop and implement human subject research protocols, vertebrate animal research protocols and design experimental procedures and documentation in accordance with the relevant laws and regulations. Prepare, clean and analyze data. Maintain optimal protocol and accuracy by conducting regular quality and reproducibility checks.
·Communicate results/findings
Draft, write, and edit scientific reports, papers, journal articles, and abstracts. Present information on research and department work to others at department meetings, journal clubs, and seminars. Present results and discuss relevant insights with Faculty and provide useful recommendations and analysis.
·Innovate and advance departmental capabilities
Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current analysis/experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all analysis and experiments. Develop, set-up, and verify new procedures in the department. Standardize and establish new published procedures; evaluate innovative techniques. Develop new protocols; design formats. Maintain an integral role in the department's meetings, presentations, and publications. Troubleshoot and correct erroneous results or problems with department software/equipment. Maintain and repair software/equipment; monitor proper use by personnel.
Assist in preparing grant applications. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve, and initiate check requests; track funding, maintain accurate balance, and resolve any discrepancies.
·Staff Leadership
May provide day-to-day functional leadership for a team or directly manage a minimal number of support staff. Establishes team goals. Gives input into, and performs employee performance reviews. Oversees and guides work assignments. Serves as the functional expert and provides guidance to the team.
·Education and Training
May serve as course master and develop new courses at the undergraduate and graduate level, including appropriate plans for evaluating student performance; may deliver lectures as a guest lecturer in courses organized by other faculty. Assist in the training of new employees. Serve as a resource and/or mentor to coworkers. Assist in the development and presentation of department training. Identify training needs and provide necessary coaching.

·Ph.D. in related discipline, MD, or equivalent degree

·PhD in Computer Science, Physics, Biomedical Informatics, Bioinformatics, Epidemiology, Biostatistics or other similar quantitative disciplines
·Experience in a related disipline.

The ideal candidate will have a doctoral degree in bioinformatics, computer science, computational biology, genomics, statistical genetics, or a related field, experience in population genetics analysis of admixed population or data simulation and imputation, programming skills in R, Perl, Python, Java, C , and Unix shell scripting, and a track record of analyzing sequence data, along with a strong work ethic, excellent written and oral communication skills, and demonstrated teamwork and multitasking skills. Experience with clinical cohorts is a plus.

Skills & Competencies
·Scientific Writing
Strong scientific writing abilities
·Programming - Basic
Working knowledge of computer programming
Strong organizational and project management skills to handle projects independently.
·Time Management
Prioritization and time-management skills sufficient to meet deadlines in a fast-paced environment
Strong analytical skills with the ability to make judgments and recommendations based on statistical analysis
·Statistics - Intermediate
Familiarity with statistical software, statistical techniques, statistical process control principles, and graphical data display
·Research Methods Skills
Designing and conducting effective research studies that address measurement, data collection, and validity issues; identifying or developing appropriate, accurate, relevant, and reliable measurement methods; drawing appropriate conclusions from study results
·Communication - Advanced
Excellent verbal, written and interpersonal communication skills.