Postdoctoral Research Fellow - Cardiovascular Genomics - Ikegami Lab


The Ikegami lab at Cincinnati Children's Hospital Medical Center is recruiting highly motivated postdocs. The Ikegami lab investigates mechanisms of gene regulation, chromosome organization, nuclear envelope functions, cardiovascular diseases, and age-associated diseases. The Ikegami lab uses diverse cutting-edge techniques in functional genomics, bioinformatics, cell engineering, stem cells, microscopy, and cardiac pathophysiology. We welcome candidates with a doctoral degree in biology, medicine, chemistry, physics, engineering, mathematics, or computer science. Candidates interested in quantitative molecular-level understanding of biology and disease processes are encouraged to apply. We also welcome candidates who wish to develop their own research agenda complementary to the current research focuses in the lab.

The Ikegami lab is in the Division of Molecular and Cardiovascular Biology at Cincinnati Children's, affiliated with the Department of Pediatrics at the University of Cincinnati. The Molecular and Cardiovascular Biology Division consists of highly collaborative research groups aiming to understand molecular principles of cardiovascular biology and diseases. Cincinnati Children's Hospital Medical Center is the third largest pediatric research institute by NIH funding in the United States and home to leading basic and translational research investigators. Postdocs enjoy world-class research facilities equipped with state-of-the-art instruments. The Office of Postdoctoral Affairs offers strong career development programs that help postdocs succeed at Cincinnati Children's.


1. Design, execute, and record laboratory experiments; apply standard scientific protocols to experiments, research, and improve current methods and evaluate innovative techniques.
2. Draft, write, and edit scientific reports, papers, journal articles, and abstracts.
3. Design and perform experiments and record data according to research protocol. Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all laboratory work and experiments.
4. Develop, set-up, and verify new procedures in the laboratory. Standardize and establish new published procedures; evaluate innovative techniques. Develop new assays and new protocols; design formats.
5. Discuss relevant insights about experimental results with Faculty and provide useful recommendations and analysis.
6. Maintain an integral role in the laboratory's meetings, presentations, and publications. Present information on research and laboratory work to others at laboratory meetings, journal clubs, and seminars.
7. Troubleshoot and correct erroneous results or problems with laboratory equipment. Maintain and repair equipment; monitor proper use by personnel.
8. Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks.
9. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests; track funding, maintain accurate balance, and resolve any discrepancies.
10. Follow policies and procedures governing the handling of confidential information as defined by Cincinnati Children's mission and applicable laws and regulations. Ensure timeliness, accuracy, availability, and security of information.
11. Perform routine procedures, including the collection and analysis of research data, which may affect decisions regarding future patient care.
12. Provide services in a manner to be regularly and conveniently available to meet the needs of Cincinnati Children's research initiatives as determined by department management and Cincinnati Children's governing body.
13. Maintain currency in field through continuing education, literature and seminars. Implement this knowledge into the Department.
14. Recommend approaches for improvement activities, recommend and perform new processes, collect and measure data, develop processes based on performance, and communicate results.
15. Ensure that work areas are organized and present a safe, accessible, effective and efficient environment. Manage attendance at required Cincinnati Children's training sessions, including radiation safety, laboratory safety, bloodborne pathogens, and OSHA. Comply with Infection Control policies and procedures.
16. Participate in establishing job requirements and goals; perform duties at the desired level of competency.
17. Understand, adhere to, and model Core Standards as defined organizationally and specifically within the department/unit.
18. Perform other duties as assigned.



Required: PhD, MD or equivalent doctoral degree.

Preferred: Recent PhD in biology, medicine, chemistry, physics, engineering, mathematics, computer science or related fields.