Cincinnati Children's Hospital Medical Center - Research Careers

Research Jobs
at Cincinnati Children's Hospital Medical Center

Full Job Title: RESEARCH FELLOW- Molecular Biology of Host-Microbe Interactions

Job Number: 82598

Location: Cincinnati, OH

Date Posted: 8-24-2016

At Cincinnati Children's, our vision is to be THE LEADER inimproving child health. Key to achieving that vision are our research programs,organized into are search foundation. Created in 1931,Cincinnati Children'sResearch Foundation is an integral part of the medical center. Today theResearch Foundation is:

· One of the largest pediatric research programs in the nation,conducting both basic and clinical research.

· Ranked second nationally among all pediatric centers receivingfunding from the National Institutes of Health.

TheAlenghat lab has an opening for a highly motivated, creative postdoctoralscientist with an interest in epigenetics, host-microbeinteractions, and the intestine. We are studying interactions with themicrobiota and molecular pathways that regulate how intestinal microbes impact mucosaland metabolic homeostasis, and chronic diseases such as inflammatory boweldisease (see Nature 2013 Dec 5;504(7478):153-7). Recent Ph.D.candidates who are curious and passionate about scientific discovery and haveexpertise in molecular biology, mouse handling, and intestinalphysiology/mucosal immunology are encouraged to apply. Experience withbioinformatics and/or gnotobiotics is also desirable.


1. Design, execute, and record laboratory experiments; applystandard scientific protocols to experiments, research, and improve currentmethods and evaluate innovative techniques.

2. Draft, write, and edit scientific reports, papers, journalarticles, and abstracts.

3. Design and perform experiments and record data according toresearch protocol. Independently reproduce, evaluate, research, and improvetechniques currently used. Adapt new methods to existing procedures and modifycurrent experiments through scientific knowledge and intuition. Maintainaccurate and detailed records of all laboratory work and experiments.

4. Develop, set-up, and verify new procedures in the laboratory.Standardize and establish new published procedures; evaluate innovativetechniques. Develop new assays and new protocols; design formats.

5. Discuss relevant insights about experimental results withFaculty and provide useful recommendations and analysis.

6. Maintain an integral role in the laboratory's meetings,presentations, and publications. Present information on research and laboratorywork to others at laboratory meetings, journal clubs, and seminars.

7. Troubleshoot and correct erroneous results or problems withlaboratory equipment. Maintain and repair equipment; monitor proper use bypersonnel.

8. Maintain optimal protocol and assay accuracy by conductingregular quality and reproducibility checks.

9. Assist in preparing, writing, and maintaining fiscal budget.Monitor expenditures and prepare capital expenditure requests; track funding,maintain accurate balance, and resolve any discrepancies.

10. Follow policies and procedures governing the handling ofconfidential information as defined by Cincinnati Children's mission andapplicable laws and regulations. Ensure timeliness, accuracy, availability, andsecurity of information.

11. Perform routine procedures, including the collection andanalysis of research data, which may affect decisions regarding future patientcare.

12. Provide services in a manner to be regularly andconveniently available to meet the needs of Cincinnati Children's researchinitiatives as determined by department management and Cincinnati Children'sgoverning body.

13. Maintain currency in field through continuing education,literature and seminars. Implement this knowledge into the Department.

14. Recommend approaches for improvement activities, recommendand perform new processes, collect and measure data, develop processes based onperformance, and communicate results.

15. Ensure that work areas are organized and present a safe,accessible, effective and efficient environment. Manage attendance at requiredCincinnati Children's training sessions, including radiation safety, laboratorysafety, blood borne pathogens, and OSHA. Comply with Infection Control policiesand procedures.

16. Participate in establishing job requirements and goals;perform duties at the desired level of competency.

17. Understand, adhere to, and model Core Standards as defined organizationallyand specifically within the department/unit.

18. Perform other duties as assigned.

EDUCATION/WORK EXPERIENCE: related discipline, MD,or equivalent required.

Recent Ph.D. candidates with expertise in molecularbiology, mouse handling, and intestinal physiology/mucosal immunology areencouraged to apply. Experience with bioinformatics and/or gnotobioticsis also desirable.

REQUIRED SKILLS: Excellent written, verbal, andinterpersonal communication skills. Demonstrate attention to detail, strongorganizational skills, supervisory ability, and an innovative approach toexperimental design. Computer literate and working knowledge of softwareapplications (word processing, spreadsheet, and database). Analytical abilitysufficient to compare data; mathematical ability sufficient to performalgebraic calculations and statistical analysis. Ability to synthesizeinformation and to create and deal with new situations by applying pastexperiences. Expressed willingness to teach others and share results. Capableof meeting time demands necessary to execute experiments.

Cincinnati Children’s is an Equal Opportunity Employer. Qualified applicants receive consideration for employment without regard to race, color, religion, sex, national origin, age, genetic information, physical or mental disability, military or veteran status, sexual orientation, gender identity/expression, or other protected status in accordance with applicable federal, state, and local laws and regulations. If you would like more information about equal employment opportunity (EEO) rights as an applicant under the law, please click here

Cincinnati Children’s will not discriminate against applicants and employee for inquiring about, discussing or disclosing their pay or, in certain circumstances, the pay of their co-workers. If you would like more information about the Pay Transparency Nondiscrimination Provision, please click here