TITLESSUPERVISED:Research Assistants, Data Analysts, Biostatisticians
TOTAL NUMBER OF FTE's DIRECTLY OR INDIRECTLY SUPERVISED: 0-4
PURPOSE OF POSITION: To learn to conduct independent research and support the independent research of others in a Medical Center dedicated to the care of infants, children, and adolescents.
A postdoctoral Computational Research Fellow position is available immediately in Dr. Emily Miraldi's lab in the Center for Systems Immunology, Divisions of Immunobiology and Biomedical Informatics (https://www.cincinnatichildrens.org/bio/m/emily-miraldi). The lab's focus is the development of computational methods to build predictive, mathematical models of the immune system from high-dimensional genomics measurements (e.g., chromatin state, single-cell gene expression data). These models will enable us to re-engineer immune-cell behavior in the context of cancer and autoimmunity. The candidate will collaborate closely with experimental colleagues in the Center for Systems Immunology and Division of Immunobiology. The team will design and execute hybrid computational-experimental strategies that push the boundaries of both immunology and computational biology.
MAJOR DUTIES AND RESPONSIBILITIES: Perform analysis and experiments: Design, execute, and record analysis and experiments; apply standard scientific protocols to research, and improve current methods and evaluate innovative techniques. Develop and implement human subject research protocols, vertebrate animal research protocols and design experimental procedures and documentation in accordance with the relevant laws and regulations. Prepare, clean and analyze data. Maintain optimal protocol and accuracy by conducting regular quality and reproducibility checks.
Communicate results/findings: Draft, write, and edit scientific reports, papers, journal articles, and abstracts. Present information on research and department work to others at department meetings, journal clubs, and seminars. Present results and discuss relevant insights with Faculty and provide useful recommendations and analysis.
Innovate and advance departmental capabilities: Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current analysis/experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all analysis and experiments. Develop, set-up, and verify new procedures in the department. Standardize and establish new published procedures; evaluate innovative techniques. Develop new protocols; design formats. Maintain an integral role in the department's meetings, presentations, and publications. Troubleshoot and correct erroneous results or problems with department software/equipment. Maintain and repair software/equipment; monitor proper use by personnel.
Financial/Budgeting: Assist in preparing grant applications. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve, and initiate check requests; track funding, maintain accurate balance, and resolve any discrepancies.
Staff Leadership: May provide day-to-day functional leadership for a team or directly manage a minimal number of support staff. Establishes team goals. Gives input into, and performs employee performance reviews. Oversees and guides work assignments. Serves as the functional expert and provides guidance to the team.
Education and Training: May serve as course master and develop new courses at the undergraduate and graduate level, including appropriate plans for evaluating student performance; may deliver lectures as a guest lecturer in courses organized by other faculty. Assist in the training of new employees. Serve as a resource and/or mentor to coworkers. Assist in the development and presentation of department training. Identify training needs and provide necessary coaching.
EDUCATION\WORK EXPERIENCE: Required:Ph.D. in related discipline, MD, or equivalent degree (a quantitative background in systems biology, engineering, computer science, statistics, math, or a related field) Preferred:Biology background is a strong plus. A willingness to develop immunology expertise as needed on the job is required.
REQUIRED SKILLS: Organization: Possess strong organization skills and attention to detail Research Methods Skills: Designing and conducting effective research studies that address measurement, data collection, and validity issues; identifying or developing appropriate, accurate, relevant, and reliable measurement methods; drawing appropriate conclusions from study results. Analysis: Strong analytical skills with the ability to make judgments and recommendations based on statistical analysis Statistics - Intermediate: Familiarity with statistical software, statistical techniques, statistical process control principles, and graphical data display Information Analysis: Time Management: Prioritization and time-management skills sufficient to meet deadlines in a fast-paced environment Communication – Advanced: Excellent verbal, written and/or interpersonal communication skills Programming – Basic: Working knowledge of programming Writing – Scientific: Strong scientific writing abilities
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